Preview

Pharmacogenetics and Pharmacogenomics

Advanced search
Фармакогенетика и Фармакогеномика_1_2022

Modern Biomarkers as Tools for Patient-Centered Medicine: Pharmacogenetics and Beyond

https://doi.org/10.37489/2588-0527-2022-1-3-4

Abstract

A priority in the development of modern healthcare is patient-centered medicine, the main tool of which is the ability to predict the individual response to certain interventions, including the use of medications. This is made possible through the use of knowledge-intensive technologies that provide the detection of certain biomarkers, making it possible to obtain individual information about the patient, in order to personalize the choice and dosing regimen of drugs. The most promising for clinical practice are pharmacogenetic/pharmacogenomic, pharmacoepigenomic and pharmacometabolomic biomarkers.

About the Authors

D. A. Sychev
Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Dr. Sci. (Med.), professor, Corresponding Member RAS, Rector,
Head Department of the Clinical Pharmacology and Therapy
named after academician B. E. Votchal

Moscow



B. I. Kantemirova
Federal State Budgetary Educational Institution of Higher Education “Astrakhan State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Dr. Sci. (Med.), professor of the Department of Pharmacology

Astrakhan



References

1. Sacristán JA. Patient-centered medicine and patient-oriented research: improving health outcomes for individual patients. BMC Med Inform Decis Mak. 2013 Jan 8;13:6. DOI: 10.1186/1472-6947-13-6

2. Sychev DA. “Multiomic” Studies as a Promising Clinical Pharmacological Tool for Personalization of Socially Significant Diseases Pharmacotherapy in Russia. Personalized Psychiatry and Neurology. 2022;2(2):1–2. DOI: 10.52667/2712-9179-2022-2-2-1-2

3. Ашихмин Я. И. Трансляционная медицина: новая надежда или коварный замысел фармацевтической промышленности? Фармакогенетика и фармакогеномика. 2015;(1):40–44. [Ashikhmin YI. Translational medicine: new hope or artful design of big pharma? Pharmacogenetics and Pharmacogenomics. 2015;(1):40–44. (In Russ).].


Review

For citations:


Sychev D.A., Kantemirova B.I. Modern Biomarkers as Tools for Patient-Centered Medicine: Pharmacogenetics and Beyond. Pharmacogenetics and Pharmacogenomics. 2022;(1):3-5. (In Russ.) https://doi.org/10.37489/2588-0527-2022-1-3-4

Views: 651


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2588-0527 (Print)
ISSN 2686-8849 (Online)