phgenomicsФармакогенетика и фармакогеномикаPharmacogenetics and Pharmacogenomics2588-05272686-8849LLC "Izdatelstvo OKI"10.24411/2588-0527-2018-10007phgenomics-46Research ArticleПЕРСОНАЛИЗИРОВАННАЯ ТЕРАПИЯPERSONALIZED THERAPYРоль персонализированной медицины в отделении реанимации и интенсивной терапииThe role of personalized medicine in the intensive care unitИвановаКсения СергеевнаIvanovaK. S.ksenia_13.1@mail.ruЦыганковаАнна ЭдуардовнаTsygankovaA. E.noemail@neicon.ruКоваленкоЮлия АнатольевнаKovalenkoY. A.noemail@neicon.ruЗаболотнаяМария СергеевнаZabolotnayaM. S.noemail@neicon.ruФедеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияFederal State Autonomous Educational Institution of Higher Education L.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovskiy University)Russian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Омский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Higher Education «Omsk State Medical University» of the Ministry of Healthcare of the Russian FederationRussian Federation201812032018013842Copyright © Иванова К.С., Цыганкова А.Э., Коваленко Ю.А., Заболотная М.С., 20182018Иванова К.С., Цыганкова А.Э., Коваленко Ю.А., Заболотная М.С.Ivanova K.S., Tsygankova A.E., Kovalenko Y.A., Zabolotnaya M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmacogenetics-pharmacogenomics.ru/jour/article/view/46

Данная статья освещает современные подходы в диагностике и лечении критических больных с точки зрения персонализированной медицины. Описаны биомаркёры таких состояний, как острая почечная недостаточность, респираторный дистресс-синдром, сепсис. Освещена роль фармакокинетики и фармакогеномики в отделении реанимации.

This article highlights modern approaches in the diagnosis and treatment of critical patients in terms of personalized medicine. Biomarkers of such conditions as acute renaL failure, acute respiratory distress syndrome, sepsis are described. The roLe of pharmacokinetics and pharmacogenomics in the intensive care unit is reported.

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The authors declare that there are no conflicts of interest present.