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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">phgenomics</journal-id><journal-title-group><journal-title xml:lang="ru">Фармакогенетика и фармакогеномика</journal-title><trans-title-group xml:lang="en"><trans-title>Pharmacogenetics and Pharmacogenomics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2588-0527</issn><issn pub-type="epub">2686-8849</issn><publisher><publisher-name>LLC "Izdatelstvo OKI"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37489/2588-0527-2022-2-24-25</article-id><article-id custom-type="elpub" pub-id-type="custom">phgenomics-261</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАРМАКОГЕНЕТИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHARMACOGENETICS STUDY</subject></subj-group></article-categories><title-group><article-title>Ассоциация генетических маркеров с развитием резистентности и нежелательных реакций при радиойодтерапии у больных раком щитовидной железы</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухамадиев</surname><given-names>Р. Х.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисенко</surname><given-names>Н. П.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Качанова</surname><given-names>А. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перфильева</surname><given-names>О. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Растворова</surname><given-names>Т. Д.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стригункова</surname><given-names>Е. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сычев</surname><given-names>Д. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства&#13;
здравоохранения Российской Федерации</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства&#13;
здравоохранения Российской Федерации; Научный центр мирового уровня «Центр персонализированной медицины»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>04</day><month>04</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>24</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мухамадиев Р.Х., Денисенко Н.П., Качанова А.А., Перфильева О.М., Растворова Т.Д., Стригункова Е.В., Сычев Д.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Мухамадиев Р.Х., Денисенко Н.П., Качанова А.А., Перфильева О.М., Растворова Т.Д., Стригункова Е.В., Сычев Д.А.</copyright-holder><copyright-holder xml:lang="en">Мухамадиев Р.Х., Денисенко Н.П., Качанова А.А., Перфильева О.М., Растворова Т.Д., Стригункова Е.В., Сычев Д.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmacogenetics-pharmacogenomics.ru/jour/article/view/261">https://www.pharmacogenetics-pharmacogenomics.ru/jour/article/view/261</self-uri><abstract><p>Цель. Изучить ассоциации между носительством полиморфизмов генов NFKB1, ATM, ATG16L2 и ATG10 иразвитием резистентности к радиойодтерапии, возникновением нежелательных реакций у больных раком щитовидной железы.  </p></abstract><kwd-group xml:lang="ru"><kwd>радиойодтерапия</kwd><kwd>полиморфизм генов</kwd><kwd>резистентность</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Perros P, Boelaert K, Colley S, et al. Guidelines for the management of thyroid cancer. Clinical Endocrinology. 2014;81:1–122. DOI: 10.1111/cen.12515.</mixed-citation><mixed-citation xml:lang="en">Perros P, Boelaert K, Colley S, et al. Guidelines for the management of thyroid cancer. Clinical Endocrinology. 2014;81:1–122. DOI: 10.1111/cen.12515.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Levy O, De la Vieja A, Carrasco N. The Na+/I- symporter (NIS): recent advances. J Bioenerg Biomembr. 1998 Apr;30(2):195–206. DOI: 10.1023/a:1020577426732.</mixed-citation><mixed-citation xml:lang="en">Levy O, De la Vieja A, Carrasco N. The Na+/I- symporter (NIS): recent advances. J Bioenerg Biomembr. 1998 Apr;30(2):195–206. DOI: 10.1023/a:1020577426732.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Silberstein EB. Reducing the incidence of 131I-induced sialadenitis: the role of pilocarpine. J Nucl Med. 2008 Apr;49(4):546–549. DOI: 10.2967/ jnumed.107.049411.</mixed-citation><mixed-citation xml:lang="en">Silberstein EB. Reducing the incidence of 131I-induced sialadenitis: the role of pilocarpine. J Nucl Med. 2008 Apr;49(4):546–549. DOI: 10.2967/ jnumed.107.049411.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Filetti S, Durante C, Hartl D, et al. Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2019 Dec 1;30(12):1856–1883. DOI: 10.1093/annonc/mdz400.</mixed-citation><mixed-citation xml:lang="en">Filetti S, Durante C, Hartl D, et al. Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2019 Dec 1;30(12):1856–1883. DOI: 10.1093/annonc/mdz400.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dyavaiah M, Rooney JP, Chittur SV, Lin Q, Begley TJ. Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1. Mol Cancer Res. 2011 Apr;9(4):462–475. DOI: 10.1158/1541-7786.MCR-10-0473.</mixed-citation><mixed-citation xml:lang="en">Dyavaiah M, Rooney JP, Chittur SV, Lin Q, Begley TJ. Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1. Mol Cancer Res. 2011 Apr;9(4):462–475. DOI: 10.1158/1541-7786.MCR-10-0473.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
