phgenomicsФармакогенетика и фармакогеномикаPharmacogenetics and Pharmacogenomics2588-05272686-8849LLC "Izdatelstvo OKI"10.37489/2588-0527-2020-2-28-29phgenomics-204Research ArticleКЛИНИЧЕСКИЙ СЛУЧАЙCASE STUDYКлинический случай генетического обследования пациентки в поздней постменопаузе: оценка полиморфизмов гена рецептора витамина D (VDR): FokI и A283G (BsmI)ВихареваА. А.
Екатеринбург
СафьяникЕ. А.
Екатеринбург
ПоповА. А.
Екатеринбург
ИзможероваН. В.
Екатеринбург
ФГБОУ ВО «Уральский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииRussian Federation202024022021022829Copyright © Вихарева А.А., Сафьяник Е.А., Попов А.А., Изможерова Н.В., 20212021Вихарева А.А., Сафьяник Е.А., Попов А.А., Изможерова Н.В.Вихарева А.А., Сафьяник Е.А., Попов А.А., Изможерова Н.В.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmacogenetics-pharmacogenomics.ru/jour/article/view/204
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дефицит витамина Dполиморфизм FokIполиморфизм A283G (BsmI)ReferencesPalomba S, Orio FJr, Russo T et al. BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial. Osteoporos Int. 2005;16(8):943-952. DOI: 10.1007/s00198-004-1800-5Palomba S, Orio FJr, Russo T et al. BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial. Osteoporos Int. 2005;16(8):943-952. DOI: 10.1007/s00198-004-1800-5Cavalcante IG, Silva AS, Costa MJ et al. Effect of vitamin D3 supplementation and influence of BsmI polymorphism of the VDR gene of the inflammatory profile and oxidative stressin elderly women with vitamin D insufficiency: Vitamin D3 megadose reduces inflammatory markers. Exp Gerontol. 2015;66:10-16. DOI: 10.1016/j.exger.2015.07.013Cavalcante IG, Silva AS, Costa MJ et al. Effect of vitamin D3 supplementation and influence of BsmI polymorphism of the VDR gene of the inflammatory profile and oxidative stressin elderly women with vitamin D insufficiency: Vitamin D3 megadose reduces inflammatory markers. Exp Gerontol. 2015;66:10-16. DOI: 10.1016/j.exger.2015.07.013Arai H, Miyamoto K, Taketani Y et al. A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res. 1997;12(6):915-921. DOI: 10.1359/jbmr.1997.12.6.915Arai H, Miyamoto K, Taketani Y et al. A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res. 1997;12(6):915-921. DOI: 10.1359/jbmr.1997.12.6.915Gentil P, de Lima Lins TC, Lima RM et al. Vitamin-D-receptor genotypes and bone-mineral density in postmenopausal women: interaction with physical activity. J Aging Phys Act. 2009;17(1):31-45. DOI: 10.1123/japa.17.1.31Gentil P, de Lima Lins TC, Lima RM et al. Vitamin-D-receptor genotypes and bone-mineral density in postmenopausal women: interaction with physical activity. J Aging Phys Act. 2009;17(1):31-45. DOI: 10.1123/japa.17.1.31Батурин А.К., Сорокина Е.Ю., Вржесинская О.А. и др. Изучение связи генетического полиморфизма rs2228570 гена VDR c обеспеченностью витамином D у жителей российской Арктики // Вопросы питания. — 2017. — Т.86. — №4. — С.77-84. DOI:10.24411/0042-8833-2017-00062.Baturin AK, Sorokina EYu, Vrzhesinskaya OA et al. The study of the association between rs2228570 polymorphism of VDR gene and vitamin D blood serum concentration in the inhabitants of the Russian Arctic. Voprosy pitaniia [Problems of Nutrition]. 2017;86(4):77-84. (In Russ). DOI:10.24411/0042-8833-2017-00062.
The authors declare that there are no conflicts of interest present.